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Endothelial Defense Pomegranate Plus


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60 Soft gels

Scientists have developed a breakthrough in the ability to maintain healthy endothelial function in aging arteries. An orally active superoxide dismutase (SOD) derived from melons (called GliSODin®) has been clinically proven to support healthy arterial function and structure while boosting levels of the body’s most powerful natural antioxidant enzymes. This patented SOD has a protective outer coating that prevents it from breaking down in the stomach’s acidic environment. This enables the SOD to be absorbed intact into the bloodstream.1,2

In a groundbreaking study, GliSODin® was shown to help support and improve vascular blood flow in middle-aged adults who had multiple risk factors for future cardiovascular problems.3

Most Life Extension members may already be obtaining a considerable amount of endothelial protection by taking SODzyme™ with GliSODin® and Wolfberry and/or taking a standardized pomegranate supplement each day. The findings about high-dose (500 mg/day) GliSODin® are so impressive that Life Extension was compelled to formulate a supplement that provides the best documented nutrients available to maintain healthy blood flow throughout the body.

1. Phytother Res. 2004 Dec;18(12):957-62.
2. J Ethnopharmacol. 2004 Sep;94(1):67-75.
3. Allerg Immunol.(Paris). 2007 Feb;39(2):45-50.


Take two capsules daily before breakfast


2 Soft Gels contain:



Total Fat

1.5 g

Total Carbohydrate

1 g

Protein <1 g

Cardiose® flavonoid glycoside [from immature sweet orange (peel)] [std. to 90% rutinoside]

500 mg

POMELLA® pomegranate extract (fruit) [std. to 30% punicalagins]

400 mg
Proprietary pomegranate blend (flower extract and seed oil) [std. to 22% punicic acid] 137.5 mg

Pomegranate 5:1 extract (fruit)

100 mg

Extramel® melon pulp concentrate (fruit) [providing 500 IU of SOD enzyme activity]

36 mg

Other ingredients: extra virgin olive oil, gelatin, glycerin, sunflower lecithin, purified water, beeswax, carob color, dextrin.


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